嗜酸性肉芽肿性多血管炎Eosinoph

Fibromyalgian.纤维性肌痛

Hypoesthesian.感觉迟钝

Electromyographyn.肌电图

Radiculopathyn.神经根病

Paraspinaladj.脊柱旁的

Bitemporaladj.双颞部的

Eosinophilian.嗜酸性(粒)细胞增多

A64-year-oldmanpresentedwithheadache,dyspnea,wheezing,cough,andnightsweats.Approximately6yearsbeforethispresentation,thepatienthadreceivedadiagnosisoffibromyalgia.Twoyearsbeforethispresentation,thepatienthadhadasuddenonsetofpainontherightsideofthelowerbackandbuttock,withhypoesthesiaandweaknessintherightleg.NeedleelectromyographyrevealedevidenceofL5radiculopathyontherightside.Thepatienthadapersistentrightfootdropandpersistenttendernessoftheparaspinalmuscles.Approximately5monthsbeforethispresentation,thepatientnotedtheonsetofacoughthatproducedthinyellowsputum.Duringthenextmonth,exertionaldyspnea,chesttightness,andwheezingdeveloped.Adiagnosisofbronchitiswasmade.Lethargy,myalgias,chills,headaches,anorexia,andnightsweatsdeveloped.Oncurrentexamination,thepatientreportedbitemporalheadaches.Evaluationrevealedeosinophilia,sinusitisonCTandabnormalresultonpulmonaryfunctiontest,includingelevatedfractiononexhalednitrateoxide.Couldthispatienthaveeosinophilicgranulomatosiswithpolyangiitis?Theconditiontypicallyoccursinmenolderthan40yearsofagewhohaveadult-onsetasthma,allergicsymptoms,neuropathy,andpulmonarysymptoms.1

一名64岁男性出现头痛、呼吸困难、哮喘、咳嗽和盗汗。此次就诊前约六年,患者诊断为纤维性肌痛。就诊前两年,患者出现突发右侧下背部和臀部疼痛,伴有右腿感觉迟钝和无力。针刺肌电图显示右侧L5神经根病变。患者出现持续性右足下垂和椎旁肌肉持续压痛。此次就诊前五个月,患者自觉开始咳嗽,带有稀薄黄色痰。随后的一个月里,出现劳力性呼吸困难、胸闷和哮喘,诊断为支气管炎。患者出现乏力、肌痛、寒战、头痛、食欲减退和夜间盗汗。体检时,患者诉双颞部头痛。检查发现嗜酸性(粒)细胞增多、CT显示鼻窦炎和异常肺功能,包括呼出气一氧化氮分数水平升高。此患者有嗜酸性肉芽肿性多血管炎可能吗?嗜酸性肉芽肿性多血管炎通常发生于40岁以上男性,出现成年起病的哮喘、过敏症状、神经病变和肺部症状。

1.常用医学词组

nightsweats盗汗

needleelectromyography

针刺肌电图

pulmonaryfunctiontest肺功能检查

fractionofexhalednitricoxide(Feno)

呼出气一氧化氮分数

nitrateoxide一氧化氮

Eosinophilicgranulomatosiswithpolyangiitis(EGP),formerlyknownastheChurg-StraussSyndrome,isasystemicvasculitis.ThisdiseasewasfirstdescribedinbyDr.JacobChurgandDr.LotteStraussasasyndromeconsistingof“asthma,eosinophilia,fever,andac







































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